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Cellular, Tissue, and Organ Bioelectricity Health and Functional Disease

Cellular potentials include resting potentials and action potentials. The height, strength and frequency of resting potentials and action potentials of a cell represent its function. First, the cell potential or resting potential and action potential (charges movement at the molecular level) determine the vitality of the cell. If the resting potential is lost, then the cell is declared dead. Second, abnormal action potentials will make the cell dysfunctional. Thus, the status of bioelectricity in cells can directly determine the functional states of an organ.

An organ is composed of different cells, some of which have active bioelectricity, while others do not. The type and quantity of the cells with active bioelectricity in organs determines the features and strength of their functions. The organs with high water content have intensive distribution of molecular charges as well as active cellular bioelectricity, so that they play a more important function in human body. Therefore, the blood, brain, glands, muscles, etc., are organs with high bioelectricity activity, while the fat, bone, tendons, connective tissue and hair are tissues with low activity in bioelectricity. 

The sum of bioelectricity generated by a variety of cells within an organ is organ bioelectricity. The decrease of action potentials in one organ will result in a decrease of strength and (or) frequency in action potentials and then a diminished or slower function. If, however, the cells in one organ increase the frequency or strength of their action potentials, then the overall function of this organ would be excessive. Take the case of the thyroid organ. A decrease in action potentials would result in hypothyroidism (too little thyroid hormone is formed and released), whereas an increase in action potentials would lead to hyperthyroidism (an excess of thyroid hormone). As another example, when the bioelectricity of skeletal muscle is a low frequency, myasthenia will occur; when the frequency becomes too low, the muscles will be paralyzed. However, when the frequency is higher than the normal, there will be spastic paralysis or seizures.